We are almost in NFL Week 10, but you still have time to prepare for the upcoming matchups. Two games that you could focus on – First is Thursday Night Football, with the Bengals facing the Ravens.

The Bengals’ offense, led by Joe Burrow, is performing well, and we expect them to excel against a struggling Ravens defense.

Next, the 49ers will play the Buccaneers, and we think the 49ers will come out on top.

NFL Week 10 Picks, Predictions

When examining the NFL odds, the matchup between the Cincinnati Bengals and Baltimore Ravens features a spread with the Bengals at -6.5 and the Ravens at +6.5.

For those looking at money line bets, the Bengals are sitting at -255, while the Ravens offer potential value at +210.

Similarly, the San Francisco 49ers are favored with a -5.5 spread against the Tampa Bay Buccaneers, who are at +5.5.

The total points over/under for the Bengals-Ravens game is set at 52.5, and for the 49ers-Buccaneers, it’s 50.5, suggesting potentially high-scoring affairs.

Let’s take a closer look.

Bengals vs. Ravens: A Clash of AFC Titans

The Bengals are charging into this game with newfound momentum. After a rough start, they’ve clawed their way back to 4-5 and are eyeing this crucial matchup to tip the scales in their favor. Winning here could mean they’re favored for the rest of their schedule.

With Joe Burrow at the helm, Cincinnati’s offense is tearing it up. In their previous encounter with the Ravens, Burrow unleashed a staggering 392 yards and five touchdowns, highlighting the Bengals’ strength through the air.

This is troublesome for the Ravens’ defense which has stumbled against passing teams, ranking in the league’s lower quarter in pass defense.

The Ravens, missing key defensive minds like former coordinator Mike Macdonald, have found themselves vulnerable but still hold their ground against the run.

As for trends, Bengals coach Zac Taylor has a solid record when up against stronger teams, while Ravens’ John Harbaugh has struggled when favored in divisional games.

With the NFL week 10 odds showing Cincinnati at +6.5, they may be the underdog, but they have a history of thriving in that role.

Joe Burrow’s track record as an underdog bodes well, as he’s consistently outperformed expectations.

This Thursday night showdown promises to be thrilling, with stakes high and both teams hungry for victory. Buckle up, it’s a game you won’t want to miss!

49ers vs. Buccaneers: A Battle of Attrition

The 49ers come off their bye ready to host the Buccaneers, and this matchup might see the return of star running back Christian McCaffrey. The bye week gave San Francisco much-needed recovery time, and McCaffrey’s return would add another dimension to their offense. If McCaffrey is back in action, expect the 49ers to exploit the Bucs’ weaknesses on defense, particularly with their effective short-passing and run game.

The Buccaneers, meanwhile, face a difficult climb. With wide receivers Mike Evans and Chris Godwin dealing with injuries, Tampa Bay’s offense has struggled to gain traction. Additionally, the Bucs’ defensive performance has been inconsistent, with limited pressure on opposing quarterbacks and lapses in coverage against short passes—two areas the 49ers are primed to capitalize on.

Historically, teams like the 49ers, who play as road favorites after a bye week, have an impressive 70% win rate when favored by more than 5.5 points. Head coach Todd Bowles has a mixed record against well-prepared teams, and his defense will need a significant boost if Tampa Bay hopes to compete with San Francisco’s balanced offensive attack.

49ers-Buccaneers Prediction: Given the 49ers’ advantages, expect them to dominate the Buccaneers with a revitalized offense and a strong defensive game plan. San Francisco looks likely to control this one from start to finish.

Additional NFL Week 10

Chiefs vs. Eagles: In a highly anticipated Super Bowl LVII rematch, the Chiefs and Eagles face off in a Monday night thriller. Both teams have continued their strong performances this season, with the Chiefs looking to solidify their lead in the AFC and the Eagles aiming to stay atop the NFC. Patrick Mahomes and Jalen Hurts bring a star-studded QB battle to the field, and fans can expect an intense showdown.

• Chiefs Odds: -3.5 favorites
• Eagles Odds: +3.5 underdogs
• Total Points Over/Under: 53.5

Bills vs. Jets: This AFC East clash has big implications, with the Bills and Jets fighting for playoff positioning. Buffalo, led by Josh Allen, is the favorite, but the Jets’ improved defense and recent offensive flashes with Breece Hall could make this a close game.

• Bills Odds: -4.5 favorites
• Jets Odds: +4.5 underdogs
• Total Points Over/Under: 47.5

Cowboys vs. Giants: NFC East rivals square off in what’s expected to be a hard-fought game. Dallas enters as the favorite, with Dak Prescott and Micah Parsons looking to lead the Cowboys in a late-season playoff push. The Giants, though underdogs, have shown flashes of competitiveness that could make this game interesting.

• Cowboys Odds: -7.5 favorites
• Giants Odds: +7.5 underdogs
• Total Points Over/Under: 49.5

Key Injuries Heading into NFL Week 10

Injuries are always a significant factor in the NFL, and heading into NFL Week 10, several teams are dealing with absences that could impact their game strategies and performance. Here’s a look at some of the most impactful injuries that could shape the NFL Week 10 outcomes:

Joe Burrow – Cincinnati Bengals

Joe Burrow has been playing through a lingering calf injury that initially slowed him down at the start of the season. While he’s back to nearly full strength, there are still questions about his mobility, especially with Cincinnati facing a relentless Ravens defense in Week 10. Fans will be watching closely to see if Burrow can maintain his usual level of play or if his calf injury will resurface under pressure.

Jalen Hurts – Philadelphia Eagles

Jalen Hurts has been dealing with a knee issue for several weeks, which has limited his mobility in recent games. Known for his dual-threat ability, Hurts’ effectiveness as a rusher has been hampered by this injury, potentially impacting the Eagles’ offensive versatility. Despite the injury, Hurts has continued to play through it, but his health will be something to monitor in the Eagles’ big Week 10 matchup against the Chiefs.

Matthew Stafford – Los Angeles Rams

Rams quarterback Matthew Stafford has been sidelined with a thumb injury that forced him out of Week 9. His availability for NFL Week 10 remains questionable, and the Rams offense has struggled without his experience and arm talent. If Stafford can’t play, Los Angeles may face a tough challenge offensively, especially as they push to stay competitive in the NFC West.

Christian McCaffrey – San Francisco 49ers

Although McCaffrey is expected to play in NFL Week 10, he’s been nursing an oblique injury that has made the 49ers cautious about his workload. The 49ers are hopeful that his time off during the bye week has helped him recover, but any limitations could affect their game plan against the Buccaneers. McCaffrey is a crucial component of San Francisco’s offense, so his health status could make a big difference.

Aaron Jones – Green Bay Packers

Packers running back Aaron Jones has been battling a hamstring injury throughout the season, leading to limited snaps in several games. He’s one of Green Bay’s most explosive players, and without him at full speed, the Packers have struggled to establish a consistent ground game. Heading into Week 10, Green Bay will need Jones healthy to boost their offensive production against a tough Steelers defense.

Darren Waller – New York Giants

The Giants’ top tight end Darren Waller has been sidelined with a hamstring injury, and his absence has been felt in New York’s passing game. Known for his athleticism and red-zone presence, Waller’s availability is uncertain for Week 10. With the Giants already facing a challenging season, his return would provide a much-needed boost to their offensive options.

Justin Jefferson – Minnesota Vikings

Star wide receiver Justin Jefferson remains on injured reserve with a hamstring injury, and while his return is eagerly anticipated, the Vikings are being cautious to avoid setbacks. His absence has been challenging for Minnesota’s offense, which has been forced to rely on younger receivers. Jefferson’s health will be a critical factor as the Vikings continue to battle for a playoff spot in the NFC.

Josh Allen – Buffalo Bills

Josh Allen has been playing through a shoulder injury that hasn’t kept him off the field but could be limiting his performance. Known for his physical style of play and willingness to scramble, Allen’s shoulder issue could impact his rushing attempts and deep throws. The Bills’ playoff hopes hinge on Allen’s health, making his injury status a key storyline for Week 10.

These injuries highlight how crucial it is for teams to have depth in their rosters and adaptability in their strategies as the season progresses.

Recapping NFL Week 9

NFL Week 9 was packed with exciting finishes, unexpected upsets, and standout performances that set the stage for an even more thrilling Week 10. Here are some of the most notable moments:

• Chiefs vs. Dolphins in Germany: The Chiefs took the win against the Dolphins, with Patrick Mahomes leading a solid offensive showing in the NFL’s first-ever game in Frankfurt, Germany. Tyreek Hill faced his former team for the first time but struggled to break through Kansas City’s tight defense, while Mahomes showcased why he’s one of the league’s most dynamic quarterbacks.
• Ravens Blowout the Seahawks: In an impressive display, the Ravens defeated the Seahawks 37-3. Lamar Jackson’s offense clicked on all cylinders, and Baltimore’s defense shut down Seattle, proving their place among the league’s top contenders.
• Eagles Edge Cowboys in NFC East Showdown: In a dramatic NFC East rivalry game, the Eagles narrowly beat the Cowboys 28-23. Jalen Hurts led a late-game drive to secure the win, keeping Philadelphia in control of the division standings.
• Bengals Defeat the Bills in Key AFC Matchup: Joe Burrow led Cincinnati to a critical victory over the Buffalo Bills, winning 24-18. With the win, the Bengals bolstered their playoff hopes, while Buffalo continues to face questions about consistency.
• Vikings Outlast Falcons in Overtime: The Vikings’ surprise win over the Falcons kept their playoff hopes alive. With Kirk Cousins sidelined Minnesota relied on backup QB Jaren Hall, who stepped up and helped his team come away with a thrilling overtime victory.

These Week 9 highlights set the tone for what promises to be an equally action-packed Week 10. As fans prepare for the games ahead, teams are gearing up to either secure their playoff positions or make pivotal adjustments for a better season outcome.